In the summer of 1998, Sayuk became an individual entrepreneur. His main activity is passenger ground transportation of urban and suburban traffic. He was also the director of the private enterprise Universal-Bud (building construction). In 2006, Oleksandr tried to become a member of parliament. In the parliamentary elections, he ran for the Karmazin Bloc. He headed the Nikopol city organization of the political party. However, Sayuk did not manage to become a parliamentarian. But four years later, he successfully ran for the Nikopol City Council. This time, Oleksandr was running as a member of the Party of Regions. In the sixth convocation of the parliament, he was a pro bono assistant to Yulia Kovalevska, a member of the Party of Regions. In 2015, Sayuk was already on the list of another party, the Revival. He failed to get into the Dnipro Regional Council, but managed to become a deputy of the Nikopol City Council for the second time. In addition, Sayuk was elected secretary of the city council. In the fall of 2020, the party “For the Future” nominated Oleksandr as a candidate for the mayoralty. In the first round, 21.86% of Nikopol residents voted for him, and 17.85% voted for his opponent from the Servant of the People party, Ruslan Oliynyk. In the second round, Sayuk was supported by 54.64% of voters. This helped him to get ahead of the candidate from the ruling political party by 13% and become the mayor of Nikopol.